Nakorn - Core Physiology - 『 ARNi มีกลไกการออกฤทธิ์ยังไง ทำไมถึงดีกับ Heart failure 』 . ถ้าใครตาม update การรักษาทางฝั่ง Cardiology ในช่วงไม่กี่ปีที่ผ่านมานี้ นอกจาก SGLT2 inhibitor ก็มีเจ้า ARNi นี่แหละครับ ที่ขยับขึ้นมาเป็น Firstline ที่เหนือกว่า ...
![Frontiers | Sacubitril-Valsartan, Clinical Benefits and Related Mechanisms of Action in Heart Failure With Reduced Ejection Fraction. A Review Frontiers | Sacubitril-Valsartan, Clinical Benefits and Related Mechanisms of Action in Heart Failure With Reduced Ejection Fraction. A Review](https://www.frontiersin.org/files/Articles/754499/fcvm-08-754499-HTML/image_m/fcvm-08-754499-g001.jpg)
Frontiers | Sacubitril-Valsartan, Clinical Benefits and Related Mechanisms of Action in Heart Failure With Reduced Ejection Fraction. A Review
ATRIUM Cardiology on X: "More data confirm improvement with early initiation of ARNI in patients admitted with ADHF 👇 For more guidance on how to transition from ACEi or ARB to ARNI,
FDA Advise-ERR: Concomitant use of Entresto and ACE inhibitors Can Lead to Serious Outcomes | Institute For Safe Medication Practices
![Practical Recommendations for the Use of Angiotensin Receptor-Neprilysin Inhibitors (ARNI) in Heart Failure: Insights from Indian Cardiologists | springermedizin.de Practical Recommendations for the Use of Angiotensin Receptor-Neprilysin Inhibitors (ARNI) in Heart Failure: Insights from Indian Cardiologists | springermedizin.de](https://media.springernature.com/lw367/springer-static/image/art%3A10.1007%2Fs40119-023-00323-8/MediaObjects/40119_2023_323_Fig10_HTML.png?as=jpg)
Practical Recommendations for the Use of Angiotensin Receptor-Neprilysin Inhibitors (ARNI) in Heart Failure: Insights from Indian Cardiologists | springermedizin.de
Pillar #2: ARNI/ACE/ARB Second pillar of QUAD Therapy for #hfref #heartfailure #cardiology #internalmedicine #medicine #familymedicine… | Instagram
![American College of Cardiology on X: "2⃣ #SGLT2i have a Class of Recommendation 2a in #HFmrEF. Weaker recommendations (COR 2b) are made for ARNi, ACEi, ARB, MRA & beta blockers in this American College of Cardiology on X: "2⃣ #SGLT2i have a Class of Recommendation 2a in #HFmrEF. Weaker recommendations (COR 2b) are made for ARNi, ACEi, ARB, MRA & beta blockers in this](https://pbs.twimg.com/media/FPR1GGqXsAM7p4T.jpg)
American College of Cardiology on X: "2⃣ #SGLT2i have a Class of Recommendation 2a in #HFmrEF. Weaker recommendations (COR 2b) are made for ARNi, ACEi, ARB, MRA & beta blockers in this
![Real-world comparative effectiveness of ARNI versus ACEi/ARB in HF with reduced or mildly reduced ejection fraction | Clinical Research in Cardiology Real-world comparative effectiveness of ARNI versus ACEi/ARB in HF with reduced or mildly reduced ejection fraction | Clinical Research in Cardiology](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs00392-022-02124-w/MediaObjects/392_2022_2124_Fig1_HTML.png)
Real-world comparative effectiveness of ARNI versus ACEi/ARB in HF with reduced or mildly reduced ejection fraction | Clinical Research in Cardiology
![Myocardial Angiotensin Metabolism in End-Stage Heart Failure | Journal of the American College of Cardiology Myocardial Angiotensin Metabolism in End-Stage Heart Failure | Journal of the American College of Cardiology](https://www.jacc.org/cms/asset/0de31856-3722-41ce-a3da-1bf68db36579/fx1.jpg)
Myocardial Angiotensin Metabolism in End-Stage Heart Failure | Journal of the American College of Cardiology
![ARNI versus ACEI/ARB in Reducing Cardiovascular Outcomes after Myocardial Infarction - She - 2021 - ESC Heart Failure - Wiley Online Library ARNI versus ACEI/ARB in Reducing Cardiovascular Outcomes after Myocardial Infarction - She - 2021 - ESC Heart Failure - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/5d96faef-034d-49f9-9a82-5e30befd8e6c/ehf213644-fig-0001-m.jpg)
ARNI versus ACEI/ARB in Reducing Cardiovascular Outcomes after Myocardial Infarction - She - 2021 - ESC Heart Failure - Wiley Online Library
![Network Meta-Analysis Comparing Angiotensin Receptor-Neprilysin Inhibitors, Angiotensin Receptor Blockers, and Angiotensin-Converting Enzyme Inhibitors in Heart Failure With Reduced Ejection Fraction - ScienceDirect Network Meta-Analysis Comparing Angiotensin Receptor-Neprilysin Inhibitors, Angiotensin Receptor Blockers, and Angiotensin-Converting Enzyme Inhibitors in Heart Failure With Reduced Ejection Fraction - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0002914922011213-ga1.jpg)
Network Meta-Analysis Comparing Angiotensin Receptor-Neprilysin Inhibitors, Angiotensin Receptor Blockers, and Angiotensin-Converting Enzyme Inhibitors in Heart Failure With Reduced Ejection Fraction - ScienceDirect
![Frontiers | Sacubitril/Valsartan: Potential Impact of ARNi “Beyond the Wall” of ACE2 on Treatment and Prognosis of Heart Failure Patients With Coronavirus Disease-19 Frontiers | Sacubitril/Valsartan: Potential Impact of ARNi “Beyond the Wall” of ACE2 on Treatment and Prognosis of Heart Failure Patients With Coronavirus Disease-19](https://www.frontiersin.org/files/MyHome%20Article%20Library/616564/616564_Thumb_400.jpg)
Frontiers | Sacubitril/Valsartan: Potential Impact of ARNi “Beyond the Wall” of ACE2 on Treatment and Prognosis of Heart Failure Patients With Coronavirus Disease-19
![Mechanism of angiotensin receptor-neprilysin inhibitor in suppression of ventricular arrhythmia - ScienceDirect Mechanism of angiotensin receptor-neprilysin inhibitor in suppression of ventricular arrhythmia - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0914508721001088-gr6.jpg)
Mechanism of angiotensin receptor-neprilysin inhibitor in suppression of ventricular arrhythmia - ScienceDirect
![Effects of angiotensin receptor‐neprilysin inhibitor on insulin resistance in patients with heart failure - Kashiwagi - 2023 - ESC Heart Failure - Wiley Online Library Effects of angiotensin receptor‐neprilysin inhibitor on insulin resistance in patients with heart failure - Kashiwagi - 2023 - ESC Heart Failure - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/18573452-891f-439d-aea9-4f3ddc037d75/ehf214352-fig-0001-m.jpg)
Effects of angiotensin receptor‐neprilysin inhibitor on insulin resistance in patients with heart failure - Kashiwagi - 2023 - ESC Heart Failure - Wiley Online Library
![From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease and Heart Failure (Part 2/5) - ScienceDirect From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease and Heart Failure (Part 2/5) - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0735109719354567-gr1.jpg)
From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease and Heart Failure (Part 2/5) - ScienceDirect
![Chronic heart failure: advances in pharmacological treatment and future perspectives | Swiss Medical Weekly Chronic heart failure: advances in pharmacological treatment and future perspectives | Swiss Medical Weekly](https://smw.ch/index.php/smw/article/download/2595/version/2595/4095/12356/2120723201393883727_w20036_f2_conv.jpg)